CD5L Protein (AA 1-347) (His tag)

Catalog No. ABIN7505645

Product Details

Target: CD5L (CD5 Molecule-Like (CD5L))

Protein Type: Recombinant

Protein Characteristics: AA 1-347

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD5L protein is labelled with His tag.

Sequence: Met1-Gly347

Characteristics: A DNA sequence encoding the Human CD5L protein (O43866) (Met1-Gly347) was expressed with a C-His.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CD5L (CD5 Molecule-Like (CD5L))

Alternative Name: CD5L (CD5L Products)

Synonyms: AIM Protein, API6 Protein, PRO229 Protein, SP-ALPHA Protein, Spalpha Protein, 1/6 Protein, AAC-11 Protein, AI047839 Protein, Api6 Protein, CT2 Protein, Pdp Protein, Sp-alpha Protein, CD5L Protein, CD5 molecule like Protein, CD5 antigen-like Protein, Cd5 molecule-like Protein, CD5 molecule-like Protein, scavenger receptor cysteine-rich domain superfamily protein-like Protein, CD5L Protein, Cd5l Protein, LOC100375137 Protein

Background:

Abbreviation: CD5L,hAIM

Target Synonym: CD5 antigen-like,Apoptosis inhibitor expressed by macrophages,hAIM,CT-2,IgM-associated peptide,SP-alpha,CD5L,API6,UNQ203/PRO229

Background: CD5 Antigen-Like (CD5L) is a soluble protein that belongs to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. CD5L is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues. It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram-negative bacteria and the SRCR domain one of CD5L retains both the LPS and LTA binding activities. Furthermore, CD5L seems to play a role as an inhibitor of apoptosis.

Molecular Weight:

Calculated MW: 38.06 kDa

Observed MW: 42 kDa

UniProt: O43866