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IL-19 Protein (AA 1-177) (His tag)

IL19 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505641
  • Target See all IL-19 (IL19) Proteins
    IL-19 (IL19) (Interleukin 19 (IL19))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-177
    Origin
    • 9
    • 4
    • 2
    Human
    Source
    • 9
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-19 protein is labelled with His tag.
    Sequence
    Met1-Ala177
    Characteristics
    A DNA sequence encoding the Human IL-19 protein (Q9UHD0) (Met1-Ala177) was expressed with a C-His.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IL19 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    IL-19 (IL19) (Interleukin 19 (IL19))
    Alternative Name
    IL-19 (IL19 Products)
    Synonyms
    IL-10C Protein, MDA1 Protein, NG.1 Protein, ZMDA1 Protein, IL19 Protein, interleukin 19 Protein, IL19 Protein, Il19 Protein
    Background

    Abbreviation: IL-19

    Target Synonym: IL-10C,Interleukin-19,MDA1,NG.1,ZMDA1

    Background: The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.

    Molecular Weight

    Calculated MW: 19.36 kDa

    Observed MW: 30 kDa

    UniProt
    Q9UHD0
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