ADAM8 Protein (AA 1-653) (His tag)
-
- Target See all ADAM8 Proteins
- ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-653
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ADAM8 protein is labelled with His tag.
- Sequence
- Met1-Ser653
- Characteristics
- A DNA sequence encoding the Human ADAM8 protein (P78325) (Met1-Ser653) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ADAM8 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))
- Alternative Name
- ADAM8 (ADAM8 Products)
- Synonyms
- CD156 Protein, MS2 Protein, CD156a Protein, E430039A18Rik Protein, adam8 Protein, reprolysin Protein, si:zc217g15.7 Protein, zgc:64059 Protein, ADAM8 Protein, RGD1566394 Protein, ADAM metallopeptidase domain 8 Protein, a disintegrin and metalloproteinase domain 8 Protein, a disintegrin and metallopeptidase domain 8 Protein, ADAM metallopeptidase domain 8a Protein, ADAM8 Protein, LOC100304737 Protein, Adam8 Protein, adam8a Protein, adam8 Protein
- Background
-
Abbreviation: ADAM8,CD156a
Target Synonym: Disintegrin and metalloproteinase domain-containing protein 8,ADAM 8,EC 3.4.24.,Cell surface antigen MS2,CD antigen CD156a,MS2
Background: ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. It can be activated and assayed under the conditions described in the Activity Assay Protocol.
- Molecular Weight
-
Calculated MW: 71.72 kDa
Observed MW: 60 kDa
- UniProt
- P78325
- Pathways
- Activation of Innate immune Response, M Phase
-