SEMA4D/CD100 Protein (AA 1-734) (His tag)
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- Target See all SEMA4D/CD100 (SEMA4D) Proteins
- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-734
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SEMA4D/CD100 protein is labelled with His tag.
- Sequence
- Met1-Arg734
- Characteristics
- A DNA sequence encoding the Human SEMA4D protein (Q92854) (Met1-Arg734) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SEMA4D Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
- Alternative Name
- Semaphorin-4D (SEMA4D Products)
- Synonyms
- C9orf164 Protein, CD100 Protein, M-sema-G Protein, SEMAJ Protein, coll-4 Protein, Semacl2 Protein, Semaj Protein, Semcl2 Protein, COLL-4 Protein, semaphorin 4D Protein, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Protein, Sema4d Protein, SEMA4D Protein
- Background
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Abbreviation: SEMA4D,CD100
Target Synonym: A8,SEMA4D,BB18,COLL4,Collapsin 4,GR3,MSEMA,Sema H,SEMA J,Semacl2,SemaH,Semcl 2
Background: Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system, Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
- Molecular Weight
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Calculated MW: 80.63 kDa
Observed MW: 90 kDa
- UniProt
- Q92854
- Pathways
- Regulation of Cell Size
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