AGT Protein (AA 1-476) (His tag)
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- Target See all AGT Proteins
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-476
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AGT protein is labelled with His tag.
- Sequence
- Met1-Glu476
- Characteristics
- A DNA sequence encoding the Human AGT protein (P01019) (Met1-Glu476) was expressed with a C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product AGT Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- Alternative Name
- AGT (AGT Products)
- Synonyms
- ANHU Protein, SERPINA8 Protein, AI265500 Protein, AngI Protein, AngII Protein, Aogen Protein, Serpina8 Protein, ANRT Protein, Ang Protein, PAT Protein, wu:fb62f06 Protein, wu:fj87b02 Protein, zgc:111892 Protein, AGT Protein, angt Protein, ANGT Protein, angiotensinogen Protein, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Protein, AGT Protein, Agt Protein, agt Protein
- Background
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Abbreviation: AGT
Target Synonym: Aangiotensinogen,Alpha 1 antiproteinase antitrypsin,Ang,Angiotensin I,Angiotensin-3,ANGT,ANHU,ANRT,AT-2,PAT,Serpin A8,SERPINA8
Background: Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
- Molecular Weight
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Calculated MW: 52.25 kDa
Observed MW: 60 kDa
- UniProt
- P01019
- Pathways
- JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
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