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IL12 Protein (AA 23-328)

IL12 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505595
  • Target See all IL12 Proteins
    IL12 (Interleukin 12 (IL12))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-328
    Origin
    • 19
    • 9
    • 4
    • 1
    Human
    Source
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Sequence
    Ile23-Ser328
    Characteristics
    A DNA sequence encoding the Human IL12(P40) Protein(P29460)(23-328)was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product IL12 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    IL12 (Interleukin 12 (IL12))
    Alternative Name
    IL12 (IL12 Products)
    Background

    Abbreviation: IL-12

    Target Synonym: Interleukin-12 subunit beta,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,Il12b,NKSF2

    Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.

    Molecular Weight

    Calculated MW: 35 kDa

    Observed MW: 38 kDa

    UniProt
    P29460
    Pathways
    JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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