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IL29 Protein (AA 1-200)

IL29 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505594
  • Target See all IL29 Proteins
    IL29 (Interleukin 29 (IL29))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-200
    Origin
    • 12
    • 1
    Human
    Source
    • 8
    • 3
    • 1
    HEK-293 Cells
    Sequence
    Met1-Thr200
    Characteristics
    A DNA sequence encoding the Human IL-29 Protein(Q8IU54)(1-200)was expressed with a polyhistidine tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product IL29 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    IL29 (Interleukin 29 (IL29))
    Alternative Name
    IL-29 (IL29 Products)
    Synonyms
    IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
    Background

    Abbreviation: IL-29

    Target Synonym: Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21

    Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

    Molecular Weight

    Calculated MW: 22 kDa

    Observed MW: 28-35 kDa

    UniProt
    Q8IU54
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