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IL1A Protein (AA 1-271)

IL1A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505592
  • Target See all IL1A Proteins
    IL1A (Interleukin 1 alpha (IL1A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-271
    Origin
    • 16
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 38
    • 13
    • 10
    • 2
    • 1
    HEK-293 Cells
    Sequence
    Met1-Ala271
    Characteristics
    A DNA sequence encoding the Human IL-1α protein (P01583) (1-271) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product IL1A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    IL1A (Interleukin 1 alpha (IL1A))
    Alternative Name
    IL-1alpha (IL1A Products)
    Background

    Abbreviation: IL-1α

    Target Synonym: IL-1 alpha,Hematopoietin-1,IL1A,IL1F1,Interleukin-1 alpha,IL1a

    Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

    Molecular Weight

    Calculated MW: 30.6 kDa

    Observed MW: 35 kDa

    UniProt
    P01583
    Pathways
    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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