SLAMF1 Protein (AA 25-345) (His tag)

Catalog No. ABIN7505558

Product Details

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Protein Type: Recombinant

Protein Characteristics: AA 25-345

Origin: Rat

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SLAMF1 protein is labelled with His tag.

Sequence: Thr 25-Ser 345

Characteristics: A DNA sequence encoding the Rat SLAMF1/CD150 / SLAM protein (D3ZAD7) (Thr 25-Ser 345) was expressed with N-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: SLAMF1 (SLAMF1 Products)

Synonyms: CD150 Protein, SLAM Protein, SLAMF1 Protein, 4933415F16 Protein, AA177906 Protein, CDw150 Protein, ESTM51 Protein, IPO-3 Protein, Slam Protein, RGD1560634 Protein, signaling lymphocytic activation molecule family member 1 Protein, SLAMF1 Protein, Slamf1 Protein

Background:

Abbreviation: SLAMF1,CD150,SLAM

Target Synonym: Signaling lymphocytic activation molecule family member 1,Slamf1,Similar to signaling lymphocytic activation molecule,

Background: CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of IFN-&gamma in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.

Molecular Weight:

Calculated MW: 35.2 kDa

Observed MW: 45 kDa

UniProt: D3ZAD7