IL28B Protein (AA 19-192) (His tag)
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- Target See all IL28B Proteins
- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-192
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL28B protein is labelled with His tag.
- Sequence
- His 19-Ala 192
- Characteristics
- A DNA sequence encoding the Rat IL-28B/IFN-lambda-3 protein (F1M3K4) (His 19-Ala 192) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL28B Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))
- Alternative Name
- IL-28B (IL28B Products)
- Synonyms
- Il28b Protein, IFL-1 Protein, IL-28B Protein, INF-alpha Protein, INF-lambda Protein, Il28 Protein, IL28B Protein, IL28C Protein, interferon, lambda 3 Protein, interferon lambda 3 Protein, Ifnl3 Protein, IFNL3 Protein
- Background
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Abbreviation: IL-28B,IFN-lambda-3
Target Synonym: Interleukin-28B,IL-28B,Cytokine Zcyto22,Interferon Lambda-3,IFN-Lambda-3,Interferon Lambda-4,IFN-Lambda-4,Interleukin-28C,IL-28C,IL28B,IFNL3,IFNL4,IL28C,ZCYTO22
Background: Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
- Molecular Weight
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Calculated MW: 19.03 kDa
Observed MW: 25 kDa
- UniProt
- F1M3K4
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