GPRC6A Protein (AA 456-590) (His tag)
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- Target See all GPRC6A products
- GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 456-590
- Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GPRC6A protein is labelled with His tag.
- Sequence
- Thr 456-Asp 590
- Characteristics
- A DNA sequence encoding the Rat GPRC6A protein (Q70VB1) (Thr 456-Asp 590) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))
- Alternative Name
- GPRC6A (GPRC6A Products)
- Synonyms
- gpcr Protein, GPCR Protein, bA86F4.3 Protein, G protein-coupled receptor class C group 6 member A Protein, G protein-coupled receptor, family C, group 6, member A Protein, G protein-coupled receptor, class C, group 6, member A Protein, GPRC6A Protein, gprc6a Protein, Gprc6a Protein
- Background
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Abbreviation: GPRC6A
Target Synonym: bA86F4.3,G protein coupled receptor 33,G-protein coupled receptor family C group 6 member A,GPC6A,GPCR33,Predicted with SOSUI analysis,seven transmembrane helix receptor
Background: Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
- Molecular Weight
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Calculated MW: 14.74 kDa
Observed MW: 25 kDa
- UniProt
- Q70VB1
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