EZH1 Protein (AA 201-400) (His tag)
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- Target See all EZH1 Proteins
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 201-400
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EZH1 protein is labelled with His tag.
- Sequence
- Lys 201-Ser 400
- Characteristics
- A DNA sequence encoding the Rat EEZH1 protein (F1LZH3) (Lys 201-Ser 400) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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Enhancer of Zeste Homolog 1 (EZH1) protein (Myc-DYKDDDDK Tag)
EZH1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- EZH1 (Enhancer of Zeste Homolog 1 (EZH1))
- Alternative Name
- EZH1 (EZH1 Products)
- Synonyms
- KMT6B Protein, si:ch211-250i3.1 Protein, zgc:136829 Protein, AW557915 Protein, mKIAA0388 Protein, EZH1 Protein, enhancer of zeste 1 polycomb repressive complex 2 subunit Protein, EZH1 Protein, ezh1 Protein, Ezh1 Protein
- Background
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Abbreviation: EZH1
Target Synonym: Enhancer of zeste homolog 1,ENX2,Histone-lysine N-methyltransferase EZH1
Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
- Molecular Weight
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Calculated MW: 21.89 kDa
Observed MW: 28 kDa
- UniProt
- F1LZH3
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