PPARA Protein (AA 280-433) (His tag)
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- Target See all PPARA Proteins
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 280-433
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PPARA protein is labelled with His tag.
- Sequence
- Ser 280-Leu 433
- Characteristics
- A DNA sequence encoding the Rat PPAR-α protein (P37230) (Ser 280-Leu 433) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PPARA Protein
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Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-258) protein (GST tag)
PPARA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-468) protein (His tag)PPARA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
- Alternative Name
- PPAR-alpha (PPARA Products)
- Synonyms
- NR1C1 Protein, PPAR Protein, PPARalpha Protein, hPPAR Protein, LOC100136415 Protein, PPARALPHA Protein, nr1c1 Protein, xPPARalpha Protein, xppara Protein, 4933429D07Rik Protein, AW742785 Protein, Nr1c1 Protein, PPAR-alpha Protein, Ppar Protein, peroxisome proliferator activated receptor alpha Protein, peroxisome proliferator-activated receptor alpha Protein, peroxisome proliferator activated receptor alpha L homeolog Protein, PPARA Protein, LOC100136415 Protein, ppara.L Protein, Ppara Protein, ppara Protein
- Background
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Abbreviation: PPAR-α
Target Synonym: PPAR alpha,PPARA,PPARalpha,PPAR-alpha,PPARMGC2452
Background: Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha , NR1C1) is a member of the Nuclear Receptor superfamily. PPAR alpha exhibits the highest affinity with unsaturated fatty acids, and linolenic acids. PPAR alpha is expressed in brown fat, liver, kidney, heart, mucosa of the stomach and duodenum, retina, adrenal gland, skeletal muscle, pancreatic islets and smooth muscle cells. PPAR alpha plays important roles in lipid and glucose metabolism, and has been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three members have been identified and are called PPAR alpha, δ, and lambda. Retinoid X Receptor (RXR) is an obligate partner for PPAR.
- Molecular Weight
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Calculated MW: 16.83 kDa
Observed MW: 18 kDa
- UniProt
- P37230
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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