Occludin Protein (OCLN) (AA 266-522) (His tag)
-
- Target See all Occludin (OCLN) Proteins
- Occludin (OCLN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 266-522
-
Origin
- Rat
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Occludin protein is labelled with His tag.
- Sequence
- Lys266-Thr522
- Characteristics
- A DNA sequence encoding the Rat OCLN protein (Q6P6T5) (Lys266-Thr522) was expressed with a N-His .
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product OCLN Protein
-
Occludin (OCLN) (AA 1-522) protein (GST tag)
OCLN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Occludin (OCLN) (AA 270-441) protein (His-IF2DI Tag)OCLN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Occludin (OCLN) (AA 423-522) protein (GST tag)OCLN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Occludin (OCLN) protein (Myc-DYKDDDDK Tag)OCLN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- Occludin (OCLN)
- Alternative Name
- Occludin (OCLN Products)
- Synonyms
- AI503564 Protein, Ocl Protein, ocln Protein, oclnb Protein, tpmt Protein, OCLN Protein, wu:fd23h10 Protein, wu:fi13c01 Protein, zgc:113992 Protein, zgc:56359 Protein, BLCPMG Protein, occludin Protein, occludin S homeolog Protein, occludin a Protein, Ocln Protein, OCLN Protein, ocln.S Protein, ocln Protein, oclna Protein
- Background
-
Abbreviation: Occludin,OCLN
Target Synonym: Occludin,OCLN_RAT,
Background: Rat Occludin is a 523 amino acid (aa), predicted molecular weight 59 kDa integral membrane protein that localizes within tight junctions of epithelial and endothelial cells. May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. May be involved in the organization of actin in endothelial cells. Defects in OCLN are the cause of band-like calcification with simplified gyration and polymicrogyria (BLCPMG), also known as pseudo-TORCH syndrome. BLCPMG is a neurologic disorder with characteristic clinical and neuroradiologic features that mimic intrauterine TORCH infection in the absence of evidence of infection. Affected individuals have congenital microcephaly, intracranial calcifications, and severe developmental delay.
- Molecular Weight
-
Calculated MW: 28.16 kDa
Observed MW: 40 kDa
- UniProt
- Q6P6T5
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
-
