Angiopoietin 1 Protein (ANGPT1) (AA 304-450) (His tag)
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- Target See all Angiopoietin 1 (ANGPT1) Proteins
- Angiopoietin 1 (ANGPT1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 304-450
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Angiopoietin 1 protein is labelled with His tag.
- Sequence
- Asn304-Ala450
- Characteristics
- A DNA sequence encoding the Rat ANG1 protein (O35460) (Asn304-Ala450) was expressed with a N-His .
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ANGPT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Angiopoietin 1 (ANGPT1)
- Alternative Name
- Angiopoietin-1 (ANGPT1 Products)
- Synonyms
- AGP1 Protein, AGPT Protein, ANG1 Protein, 1110046O21Rik Protein, Ang-1 Protein, Ang1 Protein, Agpt Protein, Agpt1 Protein, ang1 Protein, wu:fc76g06 Protein, ANG-1 Protein, angpt1 Protein, MGC80788 Protein, angiopoietin 1 Protein, angiopoietin 1 S homeolog Protein, ANGPT1 Protein, Angpt1 Protein, angpt1 Protein, angpt1.S Protein
- Background
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Abbreviation: Angiopoietin-1,ANG1
Target Synonym: AGP1,AGPT,Ang1,ANG-1,angiopoietin 1,Angiopoietin-1,ANGPT1,ANGP1_RAT
Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.
- Molecular Weight
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Calculated MW: 16.06 kDa
Observed MW: 18 kDa
- UniProt
- O35460
- Pathways
- RTK Signaling, Glycosaminoglycan Metabolic Process
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