MMP12 Protein (AA 286-463) (His tag)
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- Target See all MMP12 Proteins
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 286-463
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MMP12 protein is labelled with His tag.
- Sequence
- Ala 286-Phe 463
- Characteristics
- A DNA sequence encoding the Rat MMP-12 protein (Q63341) (Ala 286-Phe 463) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MMP12 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Alternative Name
- MMP-12 (MMP12 Products)
- Synonyms
- MMP12 Protein, AV378681 Protein, Mmel Protein, Mme Protein, HME Protein, ME Protein, MME Protein, MMP-12 Protein, matrix metallopeptidase 12 Protein, MMP12 Protein, Mmp12 Protein
- Background
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Abbreviation: MMP-12
Target Synonym: Macrophage metalloelastase,MME,Matrix metalloproteinase-12,MMP-12,Mmp12,Mme,Mmel
Background: Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
- Molecular Weight
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Calculated MW: 19.47 kDa
Observed MW: 24 kDa
- UniProt
- Q63341
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