GSTP1 Protein (AA 2-210) (His tag)
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- Target See all GSTP1 Proteins
- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-210
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GSTP1 protein is labelled with His tag.
- Sequence
- Pro 2-Gln 210
- Characteristics
- A DNA sequence encoding the rat GSTp1 protein (P04906) (Pro 2-Gln 210) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GSTP1 Protein
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Glutathione S-Transferase pi 1 (GSTP1) (AA 1-210) protein (GST tag)
GSTP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
- Alternative Name
- GSTp1 (GSTP1 Products)
- Synonyms
- DFN7 Protein, FAEES3 Protein, GST3 Protein, GSTP Protein, PI Protein, GST-P Protein, Gst3 Protein, Gstp Protein, Gstp2 Protein, gst-Pi Protein, GstpiB Protein, glutathione S-transferase P-like Protein, glutathione S-transferase pi 1 Protein, glutathione S-transferase pi 1 L homeolog Protein, glutathione S-transferase, pi 1 Protein, LOC100739163 Protein, GSTP1 Protein, Gstp1 Protein, LOC100861197 Protein, gstp1.L Protein
- Background
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Abbreviation: GSTp1
Target Synonym: Glutathione S-transferase P,Gstp1,GSTP1_RAT
Background: Glutathione S-Transferases (GSTs) are members of the phase II detoxification enzyme family that conjugate glutathione to various electrophilic compounds, including metabolites generated by oxidative processes in the body, environmental toxins or carcinogens, and anti-cancer drugs. GSTP1 is a cytosolic protein that belongs to pi class of the GST superfamily. It is crystallized as a homodimer, but also exists in solution as an equilibrium mixture of monomer and dimer, depending on the protein concentration. Four genetic variants of GSTP1 with different enzymatic activities have been identified, which indicates the particular allelic form expressed in tissues could contribute to variation in catalytic efficiency and biological functions. Genetic polymorphisms and expression patterns of GSTP1 have been associated with a variety of effects on human cancer, anti-cancer drug resistance, and asthma. In addition to its role as a drug-metabolizing enzyme, GSTP1 has ligand binding properties and regulates kinase signaling pathways through protein-protein interactions.
- Molecular Weight
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Calculated MW: 22.88 kDa
Observed MW: 31 kDa
- UniProt
- P04906
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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