NT-ProBNP Protein (AA 27-76) (GST tag)

Catalog No. ABIN7505496

Product Details

Target: NT-ProBNP (Pro-Brain Natriuretic Peptide (NT-ProBNP) (NT-ProBNP))

Protein Type: Recombinant

Protein Characteristics: AA 27-76

Origin: Rat

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NT-ProBNP protein is labelled with GST tag.

Sequence: His27-Arg76

Characteristics: A DNA sequence encoding the Rat NT-proBNP protein (P13205) (His27-Arg76) was expressed with a GST.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: NT-ProBNP (Pro-Brain Natriuretic Peptide (NT-ProBNP) (NT-ProBNP))

Alternative Name: NT-proBNP (NT-ProBNP Products)

Background:

Abbreviation: NT-proBNP

Target Synonym: Natriuretic peptides B,ANFB_RAT,Nppb,Brain natriuretic factor prohormone,preproBNP,proBNP,Gamma-brain natriuretic peptide,Iso-ANP,

Background: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis. May also function as a paracrine antifibrotic factor in the heart. Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Likely involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, kaluresis and chloruresis

Molecular Weight:

Calculated MW: 30.39 kDa

Observed MW: 30 kDa

UniProt: P13205