Calcitonin Protein (Calca) (AA 85-116) (TRX tag,His tag)
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- Target See all Calcitonin (Calca) Proteins
- Calcitonin (Calca)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 85-116
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Calcitonin protein is labelled with TRX tag,His tag.
- Sequence
- Cys85-Pro116
- Characteristics
- A DNA sequence encoding the Rat CT protein (P01257) (Cys85-Pro116) was expressed with a TRX.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Calcitonin (Calca)
- Alternative Name
- Calcitonin (Calca Products)
- Synonyms
- calcitonin-related polypeptide alpha Protein, CALCA Protein
- Background
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Abbreviation: Calcitonin,CT
Target Synonym: Calcitonin,Calca,Calc
Background: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
- Molecular Weight
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Calculated MW: 23.41 kDa
Observed MW: 22 kDa
- UniProt
- P01257
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