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MUC16 Protein (AA 6188-6372) (His tag)

CA125 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505452
  • Target See all MUC16 (CA125) Proteins
    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 6188-6372
    Origin
    • 17
    • 3
    • 2
    • 2
    Mouse
    Source
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MUC16 protein is labelled with His tag.
    Sequence
    Ile 6188-Ser 6372
    Characteristics
    A DNA sequence encoding the Mouse MUC16 protein (A0A140LJ72) (Ile 6188-Ser 6372) was expressed with N-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CA125 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
    Alternative Name
    MUC16 (CA125 Products)
    Synonyms
    CA125 Protein, 1110008I14Rik Protein, Ca125 Protein, Gm1480 Protein, RGD1308422 Protein, MUC16 Protein, mucin 16, cell surface associated Protein, mucin 16 Protein, mucin-16 Protein, MUC16 Protein, Muc16 Protein, LOC476718 Protein, LOC712735 Protein
    Background

    Abbreviation: MUC16

    Target Synonym: Mucin 16,Muc16

    Background: Mucin-16 is a heavily O-glycosylated protein that can be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus, which induces proteolytic cleavage and liberation of extracellular domain. I provides protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Mucin-16 is composed of three domains: a Serine, Threonine-rich N-terminal domain, a repeated domain containing between 12 and 60 partially conserved tandem repeats of 156 amino acids and a C-terminal transmembrane domain with a short cytoplasmic tail.

    Molecular Weight

    Calculated MW: 20.24 kDa

    Observed MW: 25 kDa

    UniProt
    A0A140LJ72
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