CD20 Protein (AA 133-291) (His tag)

Catalog No. ABIN7505448

Product Details

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Protein Type: Recombinant

Protein Characteristics: AA 133-291

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CD20 protein is labelled with His tag.

Sequence: Leu 133-Pro 291

Characteristics: A DNA sequence encoding the Mouse CD20/MS4A1 protein (P19437) (Leu 133-Pro 291) was expressed with N-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Alternative Name: CD20 (MS4A1 Products)

Synonyms: B1 Protein, Bp35 Protein, CD20 Protein, CVID5 Protein, LEU-16 Protein, MS4A2 Protein, S7 Protein, AA960661 Protein, Cd20 Protein, Ly-44 Protein, Ms4a2 Protein, MS4A1 Protein, bp35 Protein, cd20 Protein, ms4a2 Protein, leu-16 Protein, ms4a4c Protein, cd20-like Protein, membrane spanning 4-domains A1 Protein, membrane-spanning 4-domains, subfamily A, member 1 Protein, B-lymphocyte antigen CD20 Protein, MS4A1 Protein, Ms4a1 Protein, ms4a1 Protein, LOC101694281 Protein

Background:

Abbreviation: CD20,MS4A1

Target Synonym: CD20,B-lymphocyte antigen CD20,Ms4a1,B-cell differentiation antigen Ly-44,Lymphocyte antigen 44,Membrane-spanning 4-domains subfamily A member 1

Background: CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, na?ve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65 % aa sequence identity between human and mouse CD20.

Molecular Weight:

Calculated MW: 17.38 kDa

Observed MW: 28 kDa

UniProt: P19437