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CBX5 Protein (AA 1-191) (His tag)

CBX5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505415
  • Target See all CBX5 Proteins
    CBX5 (Chromobox Homolog 5 (CBX5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-191
    Origin
    Mouse
    Source
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CBX5 protein is labelled with His tag.
    Sequence
    Met 1-Ser 191
    Characteristics
    A DNA sequence encoding the Mouse HP1α protein (Q61686) (Met 1-Ser 191) was expressed with a N-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CBX5 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    CBX5 (Chromobox Homolog 5 (CBX5))
    Alternative Name
    HP1alpha (CBX5 Products)
    Synonyms
    HP1 Protein, HP1A Protein, id:ibd2026 Protein, wu:fc63e02 Protein, wu:fe47g12 Protein, wu:fi03h05 Protein, zgc:158601 Protein, CBX5 Protein, cbx5 Protein, MGC64354 Protein, 2610029O15Rik Protein, C75991 Protein, Hp1a Protein, Hp1alpha Protein, chromobox 5 Protein, chromobox homolog 5 (HP1 alpha homolog, Drosophila) Protein, chromobox 5 S homeolog Protein, CBX5 Protein, cbx5 Protein, Cbx5 Protein, cbx5.S Protein
    Background

    Abbreviation: HP1α

    Target Synonym: HP1 alpha,Antigen p25,CBX5,Chromobox 5,Epididymis luminal protein 25,HEL25,Heterochromatin protein 1,HP1A

    Background: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

    Molecular Weight

    Calculated MW: 20.9 kDa

    Observed MW: 25 kDa

    UniProt
    Q61686
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