IL1A Protein (AA 1-270) (His tag)

Catalog No. ABIN7505412

Product Details

Target: IL1A (Interleukin 1 alpha (IL1A))

Protein Type: Recombinant

Protein Characteristics: AA 1-270

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This IL1A protein is labelled with His tag.

Sequence: Met 1-Ser 270

Characteristics: A DNA sequence encoding the Mouse IL1A/IL-1A/IL-1F1 protein (P01582) (Met 1-Ser 270) was expressed with a C-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL1A (IL1A Products)

Synonyms: IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein

Background:

Abbreviation: IL1A,IL-1A,IL-1F1

Target Synonym: Interleukin-1 Alpha,IL-1 Alpha,Il1a

Background: Mouse Interleukin-1 (IL-1) designates two proteins, IL-1α and IL-1β, which are the products of distinct genes, but recognize the same cell surface receptors. IL-1α and IL-1β are structurally related polypeptides that show approximately 25 % homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.

Molecular Weight:

Calculated MW: 29.59 kDa

Observed MW: 35 kDa

UniProt: P01582

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints