VWF Protein (AA 1498-1665) (His tag)
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- Target See all VWF Proteins
- VWF (Von Willebrand Factor (VWF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1498-1665
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This VWF protein is labelled with His tag.
- Sequence
- Asp 1498-Val 1665
- Characteristics
- A DNA sequence encoding the Mouse VWF protein (Q8CIZ8) (Asp 1498-Val 1665) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product VWF Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- VWF (Von Willebrand Factor (VWF))
- Alternative Name
- VWF (VWF Products)
- Synonyms
- VWF Protein, si:ch1073-474e24.1 Protein, F8VWF Protein, VWD Protein, 6820430P06Rik Protein, AI551257 Protein, B130011O06Rik Protein, C630030D09 Protein, von Willebrand factor Protein, Von Willebrand factor Protein, VWF Protein, vwf Protein, Vwf Protein
- Background
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Abbreviation: VWF
Target Synonym: F8VWF,Von Willebrand Factor,VWD,VWF,Vwf
Background: Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.
- Molecular Weight
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Calculated MW: 18.37 kDa
Observed MW: 20 kDa
- UniProt
- Q8CIZ8
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