CHI3L1 Protein (AA 30-389) (His tag)
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- Target See all CHI3L1 Proteins
- CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-389
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CHI3L1 protein is labelled with His tag.
- Sequence
- Tyr 30-Ala 389
- Characteristics
- A DNA sequence encoding the Mouse CHI3L1/YKL40 protein (Q61362) (Tyr 30-Ala 389) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CHI3L1 Protein
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Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) (AA 22-383) protein (His tag)
CHI3L1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) (AA 30-389) protein (His tag)CHI3L1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) (AA 1-383) protein (GST tag)CHI3L1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) protein (Myc-DYKDDDDK Tag)CHI3L1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
- Alternative Name
- CHI3L1 (CHI3L1 Products)
- Synonyms
- AW208766 Protein, Brp39 Protein, Gp39 Protein, ASRT7 Protein, CGP-39 Protein, GP-39 Protein, GP39 Protein, HC-gp39 Protein, HCGP-3P Protein, YKL-40 Protein, YKL40 Protein, YYL-40 Protein, hCGP-39 Protein, GP38K Protein, CLP-1 Protein, SPC-40 Protein, SPS-40 Protein, Chil1 Protein, BP40 Protein, MGP-40 Protein, chitinase-like 1 Protein, chitinase 3 like 1 Protein, chitinase 3-like 1 (cartilage glycoprotein-39) Protein, Chil1 Protein, CHI3L1 Protein, Chi3l1 Protein
- Background
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Abbreviation: CHI3L1,YKL40
Target Synonym: AW208766,Brp39,Gp39,YKL-40,YKL40,YYL-40,hCGP-39
Background: Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.
- Molecular Weight
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Calculated MW: 39.49 kDa
Observed MW: 42 kDa
- UniProt
- Q61362
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