Hepcidin Protein (AA 59-83) (TRX tag,His tag)
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- Target See all Hepcidin (HAMP) Proteins
- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 59-83
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Hepcidin protein is labelled with TRX tag,His tag.
- Sequence
- Asp59-Thr83
- Characteristics
- A DNA sequence encoding the Mouse Hepc protein (Q9EQ21) (Asp59-Thr83) was expressed with a N terminal His-TRX tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product HAMP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
- Alternative Name
- Hepcidin (HAMP Products)
- Synonyms
- HEPC Protein, HFE2B Protein, LEAP1 Protein, PLTR Protein, Hepcidin Protein, Hamp1 Protein, Hepc Protein, Hepc1 Protein, HAMP Protein, hepcidin Protein, hamp1 Protein, hep1 Protein, hepcidin antimicrobial peptide Protein, hepcidin-like Protein, hepcidin-1 Protein, Ham percentage Protein, HAMP Protein, Hamp Protein, hamp Protein, LOC100135935 Protein, LOC106584587 Protein
- Background
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Abbreviation: Hepcidin,Hepc
Target Synonym: Hepcidin,HEPC_MOUSE,Hamp,Hamp1,Hepc,Hepc1
Background: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.
- Molecular Weight
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Calculated MW: 22.64 kDa
Observed MW: 25 kDa
- UniProt
- Q9EQ21
- Pathways
- Hormone Activity, Transition Metal Ion Homeostasis
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