SF3B3 Protein (AA 250-399) (GST tag)
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- Target See all SF3B3 Proteins
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 250-399
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SF3B3 protein is labelled with GST tag.
- Sequence
- Glu 250-Phe 399
- Characteristics
- A DNA sequence encoding the Human SF3B3 protein (Q15393-3) (Glu 250-Phe 399) was expressed with a GST tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SF3B3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Alternative Name
- SF3B3 (SF3B3 Products)
- Synonyms
- GB11574 Protein, rse1 Protein, sap130 Protein, sf3b130 Protein, staf130 Protein, sf3b3 Protein, 1810061H24Rik Protein, 5730409A01Rik Protein, AA409318 Protein, D8Ertd633e Protein, RSE1 Protein, SAP130 Protein, mKIAA0017 Protein, ik:tdsubc_2b2 Protein, wu:fb81f05 Protein, xx:tdsubc_2b2 Protein, zgc:55440 Protein, SF3b130 Protein, STAF130 Protein, splicing factor 3b subunit 3 Protein, splicing factor 3B subunit 3 Protein, splicing factor 3b, subunit 3, 130kDa Protein, splicing factor 3b subunit 3 L homeolog Protein, splicing factor 3b, subunit 3 Protein, SF3B3 Protein, LOC550935 Protein, sf3b3 Protein, Sf3b3 Protein, LOC100178056 Protein, sf3b3.L Protein
- Background
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Abbreviation: SF3B3
Target Synonym: Splicing factor 3B subunit 3,SF3B3,Spliceosome-associated protein 130
Background: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
- Molecular Weight
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Calculated MW: 41.39 kDa
Observed MW: 42 kDa
- UniProt
- Q15393-3
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