CCL28 Protein (AA 20-127) (GST-His-Tag)

Catalog No. ABIN7505322

Product Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Protein Type: Recombinant

Protein Characteristics: AA 20-127

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CCL28 protein is labelled with GST-His-Tag.

Sequence: Ser 20-Tyr 127

Characteristics: A DNA sequence encoding the Human MEC/CCL28 protein (Q9NRJ3) (Ser 20-Tyr 127) was expressed with a N-GST&C-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Alternative Name: MEC (CCL28 Products)

Synonyms: Scya28 Protein, CCL28 Protein, ccl28 Protein, nrpb Protein, enc-1 Protein, pig10 Protein, Encr-3 Protein, klhl35 Protein, Xencr-3 Protein, tp53i10 Protein, LOC100303767 Protein, CCK1 Protein, MEC Protein, SCYA28 Protein, C-C motif chemokine ligand 28 Protein, ectodermal-neural cortex 1 (with BTB domain) Protein, C-C motif chemokine 28 Protein, chemokine (C-C motif) ligand 28 Protein, Ccl28 Protein, CCL28 Protein, ccl28 Protein, enc1 Protein, LOC100303767 Protein

Background:

Abbreviation: MEC,CCL28

Target Synonym: C-C Motif Chemokine 28,Mucosae-Associated Epithelial Chemokine,MEC,Protein CCK1,Small-Inducible Cytokine A28,CCL28,SCYA28

Background: Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83 % sequence identity in their mature regions.

Molecular Weight:

Calculated MW: 36.77 kDa

Observed MW: 38 kDa

UniProt: Q9NRJ3