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Fibronectin Protein (AA 32-230) (GST-His-Tag)

Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505313
  • Target See all Fibronectin Proteins
    Fibronectin
    Protein Type
    Recombinant
    Protein Characteristics
    AA 32-230
    Origin
    • 17
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Source
    • 20
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Fibronectin protein is labelled with GST-His-Tag.
    Sequence
    Gln 32-Arg 230
    Characteristics
    A DNA sequence encoding the Human Fibronectin protein (P02751) (Gln 32-Arg 230) was expressed with a N-GST&C-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product Fibronectin Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    Fibronectin
    Abstract
    Fibronectin Products
    Synonyms
    FN Protein, cig Protein, fibronectin Protein, finc Protein, lets Protein, msf Protein, CIG Protein, ED-B Protein, FINC Protein, FNZ Protein, GFND Protein, GFND2 Protein, LETS Protein, MSF Protein, E330027I09 Protein, Fn Protein, Fn-1 Protein, FIBNEC Protein, fn-1 Protein, fibronectin 1 Protein, FN1 Protein, fn1 Protein, Fn1 Protein
    Background

    Abbreviation: Fibronectin

    Target Synonym: Fibronectin,FN1,CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF

    Background: Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

    Molecular Weight

    Calculated MW: 46.78 kDa

    Observed MW: 50 kDa

    UniProt
    P02751
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