Lipoprotein Lipase Protein (LPL) (AA 28-475) (His tag)
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- Target See all Lipoprotein Lipase (LPL) Proteins
- Lipoprotein Lipase (LPL)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-475
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Lipoprotein Lipase protein is labelled with His tag.
- Sequence
- Ala 28-Gly 475
- Characteristics
- A DNA sequence encoding the Human LPL protein (P06858) (Ala 28-Gly 475) was expressed with a N-HIS tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product LPL Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Lipoprotein Lipase (LPL)
- Alternative Name
- LPL (LPL Products)
- Synonyms
- HDLCQ11 Protein, LIPD Protein, fb62e04 Protein, fc49b03 Protein, wu:fb62e04 Protein, wu:fc49b03 Protein, LPL Protein, lipd Protein, hdlcq11 Protein, lpl Protein, LOC100223817 Protein, lipoprotein lipase Protein, LPL Protein, Lpl Protein, lpl Protein
- Background
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Abbreviation: LPL
Target Synonym: LIPL,Lipoprotein lipase (LPL),LPL LIPD
Background: LPL (LipoProtein Lipase, also LIPD) is a 53-56 kDa glycoprotein member of the Lipase family, AB Hydrolase superfamily of molecules. It is produced by multiple cell types, including adipocytes, skelelal muscle cells and macrophages. Once secreted, the circulating enzyme ultimately becomes immobilized on the surface of endothelium by binding to cell surface heparan sulfate. Here, it hydrolyzes triglycerides embedded in chylomicrons and VLDLs by homodimerizing and interacting with apoC2.
- Molecular Weight
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Calculated MW: 49.17 kDa
Observed MW: 55 kDa
- UniProt
- P06858
- Pathways
- Lipid Metabolism
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