MCM5 Protein (AA 1-200) (His tag)
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- Target See all MCM5 Proteins
- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-200
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MCM5 protein is labelled with His tag.
- Sequence
- Met 1-Asp 200
- Characteristics
- A DNA sequence encoding the Human MCM5 protein (P33992) (Met 1-Asp 200) was expressed with a C-His,N-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MCM5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
- Alternative Name
- MCM5 (MCM5 Products)
- Synonyms
- 23.m06024 Protein, cdc46 Protein, xmcm5 Protein, CDC46 Protein, P1-CDC46 Protein, Afu5g02520 Protein, NCU01171.1 Protein, AA617332 Protein, AI324988 Protein, AL033333 Protein, Cdc46 Protein, Mcmd5 Protein, mCD46 Protein, mCDC46 Protein, mcm5 Protein, wu:fb34a06 Protein, CG4082 Protein, DmCDC46 Protein, DmCDC465 Protein, DmMCM5 Protein, DmMcm5 Protein, DmeMCM5 Protein, Dmel\\CG4082 Protein, MCM5 Protein, McM5 Protein, PCR4 Protein, DNA replication licensing factor MCM5 Protein, minichromosome maintenance complex component 5 S homeolog Protein, minichromosome maintenance complex component 5 Protein, DNA replication licensing factor Mcm5 Protein, DNA replication licensing factor mcm5 Protein, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) Protein, minichromosome maintenance complex component 5 L homeolog Protein, Minichromosome maintenance 5 Protein, DNA replication licensing factor mcm-5 Protein, BBOV_IV010040 Protein, mcm5.S Protein, MCM5 Protein, AFUA_5G02520 Protein, NCU01171 Protein, PVX_084615 Protein, LOC5576119 Protein, CpipJ_CPIJ008678 Protein, Bm1_24480 Protein, CMU_022890 Protein, Mcm5 Protein, mcm5 Protein, TP01_0722 Protein, mcm5.L Protein, mcm-5 Protein
- Background
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Abbreviation: MCM5
Target Synonym: DNA replication licensing factor MCM5,MCM5, CDC46
Background: MCM5 (Mini Chromosome Maintainance protein-5) is involved in the control of DNA replication. MCM proteins have DNA dependent ATPase motifs in their central domain which is conserved from yeast to mammals. MCM proteins form a complex which exhibits ATPase and helicase activities. In G0 phase levels of MCM 2 and 5 are lower than that of MCM7 and 3 but increase as the cell enters G1/S phase of the cell cycle. It has been reported that immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy.
- Molecular Weight
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Calculated MW: 21.89 kDa
Observed MW: 35 kDa
- UniProt
- P33992-1
- Pathways
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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