MCM8 Protein (AA 1-250) (His tag)
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- Target See all MCM8 Proteins
- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-250
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MCM8 protein is labelled with His tag.
- Sequence
- Met 1-Ser 250
- Characteristics
- A DNA sequence encoding the Human MCM8 protein (Q9UJA3) (Met 1-Ser 250) was expressed with a C-His,N-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MCM8 Protein
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Minichromosome Maintenance Deficient 8 (MCM8) (AA 646-735) protein (GST tag)
MCM8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Minichromosome Maintenance Deficient 8 (MCM8) (AA 1-840) protein (GST tag)MCM8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
- Alternative Name
- MCM8 (MCM8 Products)
- Synonyms
- C20orf154 Protein, dJ967N21.5 Protein, 5730432L01Rik Protein, minichromosome maintenance 8 homologous recombination repair factor Protein, minichromosome maintenance 8 homologous recombination repair factor L homeolog Protein, MCM8 Protein, Mcm8 Protein, mcm8.L Protein
- Background
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Abbreviation: MCM8
Target Synonym: DNA helicase MCM8,MCM8,Minichromosome maintenance 8
Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.
- Molecular Weight
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Calculated MW: 27.39 kDa
Observed MW: 35 kDa
- UniProt
- Q9UJA3-1
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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