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NOTCH3 Protein (AA 1289-1458) (His tag)

NOTCH3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505274
  • Target See all NOTCH3 Proteins
    NOTCH3 (Notch 3 (NOTCH3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1289-1458
    Origin
    • 11
    • 5
    Human
    Source
    • 8
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This NOTCH3 protein is labelled with His tag.
    Sequence
    Val 1289-Cys 1458
    Characteristics
    A DNA sequence encoding the Human NOTCH3 protein (Q9UM47) (Val 1289-Cys 1458) was expressed with a N-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product NOTCH3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Alternative Name
    NOTCH3 (NOTCH3 Products)
    Synonyms
    CADASIL Protein, CASIL Protein, IMF2 Protein, AW229011 Protein, N3 Protein, hpbk Protein, fa14b08 Protein, notch5 Protein, wu:fa14b08 Protein, notch 3 Protein, NOTCH3 Protein, Notch3 Protein, notch3 Protein
    Background

    Abbreviation: NOTCH3

    Target Synonym: Neurogenic locus notch homolog protein 3,NOTCH3

    Background: Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes . The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. In both vertebrates and invertebrates, Notch signaling is important for specifying cell fates and for defining boundaries between different cell types.

    Molecular Weight

    Calculated MW: 18.59 kDa

    Observed MW: 20 kDa

    UniProt
    Q9UM47
    Pathways
    Notch Signaling
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