PAK6 Protein (AA 1-681) (His tag)
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- Target See all PAK6 Proteins
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-681
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PAK6 protein is labelled with His tag.
- Sequence
- Met 1-Cys 681
- Characteristics
- A DNA sequence encoding the Human PAK6 protein (Q9NQU5) (Met 1-Cys 681) was expressed with a N-His&C-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PAK6 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Alternative Name
- PAK6 (PAK6 Products)
- Synonyms
- PAK5 Protein, 4732456M09 Protein, pak6 Protein, si:ch211-158b22.3 Protein, p21 (RAC1) activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6b Protein, PAK6 Protein, Pak6 Protein, pak6b Protein
- Background
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Abbreviation: PAK6
Target Synonym: Serine/threonine-protein kinase PAK 6,PAK6,p21-activated kinase 6 (PAK-6)
Background: As downstream targets of the Rho GTPases, the p21-activated kinase (PAK) family of serine/threonine kinases regulates the organization of the actin cytoskeleton in mammalian cells. The PAK family is structurally categorized in two groups, each with three members: group I PAK1-3, and group II PAK4-6. PAK6 is expressed most highly in brain and testes, with lower levels in multiple tissues. Both MKK6 and p38 MAPK activate PAK6, suggesting a role for this kinase in the cellular stress response.
- Molecular Weight
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Calculated MW: 74.8 kDa
Observed MW: 80 kDa
- UniProt
- Q9NQU5
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