RAB38 Protein (AA 1-211) (His tag)

Catalog No. ABIN7505254

Product Details

Target: RAB38 (RAB38, Member RAS Oncogene Family (RAB38))

Protein Type: Recombinant

Protein Characteristics: AA 1-211

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RAB38 protein is labelled with His tag.

Sequence: Met 1-Ser 211

Characteristics: A DNA sequence encoding the Human RAB38 protein (P57729) (Met 1-Ser 211) was expressed with a N-His&C-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: RAB38 (RAB38, Member RAS Oncogene Family (RAB38))

Alternative Name: RAB38 (RAB38 Products)

Synonyms: RAB38 Protein, rab38 Protein, 2310011F14Rik Protein, AU043391 Protein, cht Protein, NY-MEL-1 Protein, rrGTPbp Protein, R Protein, Ruby Protein, RAB38, member RAS oncogene family Protein, RAB38a, member RAS oncogene family Protein, RAB38, member RAS oncogene family S homeolog Protein, RAB38 Protein, rab38a Protein, rab38.S Protein, Rab38 Protein

Background:

Abbreviation: RAB38

Target Synonym: RAB38,Ras-related protein Rab-38,Melanoma antigen NY-MEL-1

Background: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes, the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).

Molecular Weight:

Calculated MW: 23.1 kDa

Observed MW: 29 kDa

UniProt: P57729