ZIC3 Protein (AA 1-467) (His tag)
-
- Target See all ZIC3 Proteins
- ZIC3 (Zic Family Member 3 (ZIC3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-467
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ZIC3 protein is labelled with His tag.
- Sequence
- Met 1-Val467
- Characteristics
- A DNA sequence encoding the Human Zic3 protein (O60481) (Met 1-Val467) was expressed with aN-His&C-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ZIC3 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- ZIC3 (Zic Family Member 3 (ZIC3))
- Alternative Name
- Zic3 (ZIC3 Products)
- Synonyms
- HTX Protein, HTX1 Protein, VACTERLX Protein, ZNF203 Protein, RGD1561261 Protein, zic3-A Protein, Bn Protein, Zic family member 3 Protein, Zic family member 3 S homeolog Protein, zinc finger protein of the cerebellum 3 Protein, ZIC3 Protein, Zic3 Protein, zic3.S Protein
- Background
-
Abbreviation: Zic3
Target Synonym: Zinc finger protein ZIC 3,ZIC3,Zinc finger protein 203,Zinc finger protein of the cerebellum 3
Background: ZIC3 (zinc-finger protein of the cerebellum 3) is a 50 kDa (predicted) member of the GLI C2H2-type Zn-finger protein family. It is expressed in cerebellum, and apparently plays a key role in left-right body axis formation. Human ZIC3 is 467 amino acids (aa) in length. It contains N?terminal poly-Ala (aa 46?55) and poly-His (aa 87?97) segments, followed by five C2H2-type Zn-fingers (aa 253?410). Within the zinc finger region, there is an overlapping NES (aa 290?349) and two NLS's (aa 367?382 and 403?410). ZIC3 reportedly binds to GLI-3.
- Molecular Weight
-
Calculated MW: 51.26 kDa
Observed MW: 52 kDa
- UniProt
- O60481
-