ATXN7L1 Protein (AA 1-146) (His tag)
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- Target See all ATXN7L1 products
- ATXN7L1 (Ataxin 7-Like 1 (ATXN7L1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-146
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ATXN7L1 protein is labelled with His tag.
- Sequence
- Met 1- Ala 146
- Characteristics
- A DNA sequence encoding the Human ATXN7L1 protein (Q9ULK2-2) (Met 1- Ala 146) was expressed with a C-His,N-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- ATXN7L1 (Ataxin 7-Like 1 (ATXN7L1))
- Alternative Name
- ATXN7L1 (ATXN7L1 Products)
- Synonyms
- ATXN7L4 Protein, 2810423G08Rik Protein, Atxn7l4 Protein, ATXN7L1 Protein, RGD1305730 Protein, RGD1564242 Protein, ataxin 7 like 1 Protein, ataxin 7-like 1 Protein, ataxin-7-like protein 1 Protein, ATXN7L1 Protein, Atxn7l1 Protein, atxn7l1 Protein, LOC100598692 Protein
- Background
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Abbreviation: ATXN7L1
Target Synonym: Ataxin-7-like protein 1,ATXN7L1,Ataxin-7-like protein 1,Ataxin-7-like protein 4
Background: ATXN7 is found in the cytoplasm of all the populations of neurons analyzed in control brains, but nuclear labeling is observed in some neurons with a frequency and intensity weakly correlated with the topography of lesions in patients. Ataxin-7 is a component of the Tata binding protein (TBP)-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA), which is implicated in several steps of transcriptional regulation such as histone acetylation/deubiquitinylation and recruitment of the preinitiation complex to promoters.
- Molecular Weight
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Calculated MW: 15.95 kDa
Observed MW: 20 kDa
- UniProt
- Q9ULK2-2
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