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GABRB3 Protein (AA 26-245) (His tag)

GABRB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505216
  • Target See all GABRB3 Proteins
    GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 26-245
    Origin
    • 4
    • 3
    Human
    Source
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GABRB3 protein is labelled with His tag.
    Sequence
    Ser 26-Tyr 245
    Characteristics
    A DNA sequence encoding the Human GABRβ3(GABRB3) protein (P28472) (Ser 26-Tyr 245) was expressed with a C-His and N-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product GABRB3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
    Abstract
    GABRB3 Products
    Synonyms
    GABRB3 Protein, eca5 Protein, LOC100230475 Protein, ECA5 Protein, A230092K12Rik Protein, AW049585 Protein, Cp1 Protein, Gabrb-3 Protein, beta3 Protein, gamma-aminobutyric acid type A receptor beta3 subunit Protein, gamma-aminobutyric acid (GABA) A receptor, beta 3 Protein, gamma-aminobutyric acid type A receptor beta 3 subunit Protein, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Protein, GABRB3 Protein, gabrb3 Protein, Gabrb3 Protein
    Background

    Abbreviation: GABRβ3

    Target Synonym: Gamma-aminobutyric acid receptor subunit beta-3,GABRB3,GABA(A) receptor subunit beta-3,GABRB3

    Background: γ-aminobutyric acid type A receptor β3 subunit (GABRB3) is a candidate gene for autism spectrum conditions (ASC). Alteration in the gene results in increased tactile sensitivity, or hypersensitivity.Overexpression of GABRB3 might be implicated in the pathogenesis of heroin dependence. Aberration or mutation of this gene leads to neurodevelopmental disorders, such as Angelman syndrome, Prader-Willi syndrome and schizophrenia.[1][3] GABRB3 polymorphisms results in nonsyndromic cleft lip and/or palate (NSCL/P).

    Molecular Weight

    Calculated MW: 24.09 kDa

    Observed MW: 32 kDa

    UniProt
    P28472
    Pathways
    Sensory Perception of Sound
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