GABRB3 Protein (AA 26-245) (His tag)
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- Target See all GABRB3 Proteins
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-245
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GABRB3 protein is labelled with His tag.
- Sequence
- Ser 26-Tyr 245
- Characteristics
- A DNA sequence encoding the Human GABRβ3(GABRB3) protein (P28472) (Ser 26-Tyr 245) was expressed with a C-His and N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GABRB3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Abstract
- GABRB3 Products
- Synonyms
- GABRB3 Protein, eca5 Protein, LOC100230475 Protein, ECA5 Protein, A230092K12Rik Protein, AW049585 Protein, Cp1 Protein, Gabrb-3 Protein, beta3 Protein, gamma-aminobutyric acid type A receptor beta3 subunit Protein, gamma-aminobutyric acid (GABA) A receptor, beta 3 Protein, gamma-aminobutyric acid type A receptor beta 3 subunit Protein, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Protein, GABRB3 Protein, gabrb3 Protein, Gabrb3 Protein
- Background
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Abbreviation: GABRβ3
Target Synonym: Gamma-aminobutyric acid receptor subunit beta-3,GABRB3,GABA(A) receptor subunit beta-3,GABRB3
Background: γ-aminobutyric acid type A receptor β3 subunit (GABRB3) is a candidate gene for autism spectrum conditions (ASC). Alteration in the gene results in increased tactile sensitivity, or hypersensitivity.Overexpression of GABRB3 might be implicated in the pathogenesis of heroin dependence. Aberration or mutation of this gene leads to neurodevelopmental disorders, such as Angelman syndrome, Prader-Willi syndrome and schizophrenia.[1][3] GABRB3 polymorphisms results in nonsyndromic cleft lip and/or palate (NSCL/P).
- Molecular Weight
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Calculated MW: 24.09 kDa
Observed MW: 32 kDa
- UniProt
- P28472
- Pathways
- Sensory Perception of Sound
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