SLC2A6 Protein (AA 216-289) (GST-His-Tag)
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- Target See all SLC2A6 products
- SLC2A6 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 6 (SLC2A6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 216-289
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SLC2A6 protein is labelled with GST-His-Tag.
- Sequence
- Asn 216-Thr 289
- Characteristics
- A DNA sequence encoding the Human GLUT6(SLC2A6) protein (Q9UGQ3) (Asn 216-Thr 289) was expressed with a N-GST and C-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 6 (SLC2A6) protein (Myc-DYKDDDDK Tag)
SLC2A6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- SLC2A6 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 6 (SLC2A6))
- Alternative Name
- GLUT6 (SLC2A6 Products)
- Synonyms
- A330096C23 Protein, F630103L12Rik Protein, Glut6 Protein, Glut9 Protein, glut6 Protein, glut9 Protein, MGC82056 Protein, SLC2A6 Protein, si:dkey-104n9.2 Protein, GLUT6 Protein, GLUT9 Protein, HSA011372 Protein, solute carrier family 2 (facilitated glucose transporter), member 6 Protein, solute carrier family 2 member 6 Protein, solute carrier family 2 (facilitated glucose transporter), member 6 L homeolog Protein, Slc2a6 Protein, SLC2A6 Protein, slc2a6.L Protein, slc2a6 Protein
- Background
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Abbreviation: GLUT6,SLC2A6
Target Synonym: Solute carrier family 2,facilitated glucose transporter member 6,SLC2A6,Glucose transporter type 6,GLUT6
Background: GLUT6 as a functionally uncharacterized transporter that putatively works in inflammatory responses. Inflammatory stimuli increase GLUT6 expression level, although GLUT6-knockout mice exhibit a subtle phenotype to lipopolysaccharide administration. Metabolomics and in vitro analyses show that GLUT6 functions as a glycolysis modulator in inflammatory macrophages. GLUT6 does not mediate glucose uptake and is localized on lysosomal membranes. We conclude that GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates inflammatory responses by affecting the metabolic shift in macrophages.
- Molecular Weight
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Calculated MW: 33.03 kDa
Observed MW: 35 kDa
- UniProt
- Q9UGQ3-1
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