RCAS1 Protein (AA 28-213) (His tag)

Catalog No. ABIN7505209

Product Details

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Protein Type: Recombinant

Protein Characteristics: AA 28-213

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RCAS1 protein is labelled with His tag.

Sequence: Arg 28-Ser 213

Characteristics: A DNA sequence encoding the Human RCAS1 / EBAG9 protein (O00559) (Arg 28-Ser 213) was expressed with N-His.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Alternative Name: RCAS1 (EBAG9 Products)

Synonyms: EB9 Protein, PDAF Protein, MGC56608 Protein, zgc:56608 Protein, MGC84425 Protein, EBAG9 Protein, AI835379 Protein, Rcas1 Protein, RCAS1 Protein, eb9 Protein, pdaf Protein, rcas1 Protein, estrogen receptor binding site associated, antigen, 9 Protein, estrogen receptor binding site associated, antigen, 9 L homeolog Protein, estrogen receptor-binding fragment-associated gene 9 Protein, EBAG9 Protein, ebag9 Protein, ebag9.L Protein, Ebag9 Protein

Background:

Abbreviation: RCAS1,EBAG9

Target Synonym: Receptor-binding cancer antigen expressed on SiSo cells,EBAG9,RCAS1,Cancer-associated surface antigen RCAS1,Estrogen receptor-binding fragment-associated gene 9 protein

Background: RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

Molecular Weight:

Calculated MW: 20.35 kDa

Observed MW: 39 kDa

UniProt: O00559