LDHB Protein (AA 2-334) (His tag)

Catalog No. ABIN7505203

Product Details

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Protein Type: Recombinant

Protein Characteristics: AA 2-334

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This LDHB protein is labelled with His tag.

Sequence: Ala 2-Leu334

Characteristics: A DNA sequence encoding the Human LDHB protein (P07195) (2A-334L) was expressed with N-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Alternative Name: LDHB (LDHB Products)

Synonyms: LDH-B Protein, LDH-H Protein, LDHBD Protein, TRG-5 Protein, AI790582 Protein, H-Ldh Protein, Ldh-2 Protein, Ldh2 Protein, ldh-h Protein, ldh2 Protein, ldhb Protein, ldhba Protein, trg-5 Protein, LDHB Protein, LDH-B-A Protein, wu:fa16d07 Protein, wu:fa20c10 Protein, wu:fa96a08 Protein, LDH-B-B Protein, zgc:92882 Protein, lactate dehydrogenase B Protein, lactate dehydrogenase B S homeolog Protein, lactate dehydrogenase Ba Protein, lactate dehydrogenase Bb Protein, LDHB Protein, Ldhb Protein, ldhb.S Protein, ldhb Protein, ldhba Protein, ldhbb Protein

Background:

Abbreviation: LDHB

Target Synonym: L-lactate Dehydrogenase B Chain,LDH-B,LDH Heart Subunit,LDH-H,Renal Carcinoma Antigen NY-REN-46,LDHB

Background: L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C, members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver. It is also called Hydroxybutyrate Dehydrogenase (HBD) due to its ability to catalyze the oxidation of hydroxybutyrate.

Molecular Weight:

Calculated MW: 36.52 kDa

Observed MW: 40 kDa

UniProt: P07195

Pathways: Warburg Effect