L-Selectin Protein (AA 39-332) (His tag)
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- Target See all L-Selectin (SELL) Proteins
- L-Selectin (SELL) (Selectin L (SELL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 39-332
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This L-Selectin protein is labelled with His tag.
- Sequence
- Trp 39-Asn 332
- Characteristics
- A DNA sequence encoding the Human CD62L/L-Selectin protein (P30836) (Trp 39-Asn 332) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SELL Protein
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Selectin L (SELL) (AA 39-332) protein (His tag)
SELL Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin L (SELL) (AA 39-332) protein (His tag)SELL Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Selectin L (SELL) (AA 190-332) protein (His tag)SELL Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin L (SELL) (AA 29-332) protein (His tag)SELL Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Selectin L (SELL) (AA 1-375) protein (GST tag)SELL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Selectin L (SELL) (Active) protein (His tag,Fc Tag)SELL Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Alternative Name
- CD62L (SELL Products)
- Synonyms
- CD62L Protein, LAM1 Protein, LECAM1 Protein, LEU8 Protein, LNHR Protein, LSEL Protein, LYAM1 Protein, PLNHR Protein, TQ1 Protein, A.11 Protein, L-selectin Protein, LECAM-1 Protein, SELE Protein, AI528707 Protein, Lnhr Protein, Ly-22 Protein, Ly-m22 Protein, Lyam-1 Protein, Lyam1 Protein, selectin L Protein, selectin, lymphocyte Protein, SELL Protein, Sell Protein
- Background
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Abbreviation: CD62L,L-Selectin
Target Synonym: L-selectin,Sell,CD62 antigen-like family member L,Leukocyte adhesion molecule 1 (LAM-1),Leukocyte-endothelial cell adhesion molecule 1,Lymph node homing receptor,Lymphocyte antigen 22 (Ly-22),Lymphocyte surface MEL-14 antigen,CD62L
Background: L-Selectin (also known as Leukocyte Selectin, LAM?1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L), a member of the Selectin family, is a cell surface glycoprotein expressed constitutively on a wide variety of leukocytes. Two forms of L?Selectin have been reported, apparently arising as a result of post-translational modifications. The lymphocyte form shows an apparent molecular weight of 74 kDa, while the neutrophil form is 90 - 100 kDa. Human and mouse L?Selectin share 76 % amino acid (aa) sequence homology.L?Selectin plays a role in the migration of lymphocytes into peripheral lymph nodes and sites of chronic inflammation, and of neutrophils into acute inflammatory sites. Acting in cooperation with P-Selectin and E-Selectin, L?Selectin mediates the initial interaction of circulating leukocytes with endothelial cells that produces a characteristic "rolling" of the leukocytes on the endothelium. This initial interaction, also involving ICAM-1 and VCAM-1, leads eventually to extravasation of the white blood cell through the blood vessel wall into the extracellular matrix tissue.
- Molecular Weight
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Calculated MW: 32.23 kDa
Observed MW: 39 kDa
- UniProt
- P30836
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