TRAPPC8 Protein (AA 100-250) (His tag)
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- Target See all TRAPPC8 products
- TRAPPC8 (Trafficking Protein Particle Complex 8 (TRAPPC8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 100-250
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TRAPPC8 protein is labelled with His tag.
- Sequence
- Gly 100-Gln 250
- Characteristics
- A DNA sequence encoding the Human TRAPPC8 protein (Q9Y2L5) (Gly 100-Gln 250) was expressed with a C-His and N-His.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- TRAPPC8 (Trafficking Protein Particle Complex 8 (TRAPPC8))
- Alternative Name
- TRAPPC8 (TRAPPC8 Products)
- Synonyms
- GSG1 Protein, HsT2706 Protein, KIAA1012 Protein, TRS85 Protein, 5033403J15Rik Protein, AI845423 Protein, D030074E01Rik Protein, Trs85 Protein, mKIAA1012 Protein, RGD1309102 Protein, MGC68974 Protein, kiaa1012 Protein, MGC160116 Protein, MGC146498 Protein, trafficking protein particle complex 8 Protein, trafficking protein particle complex 8 L homeolog Protein, TRAPPC8 Protein, Trappc8 Protein, trappc8.L Protein, trappc8 Protein
- Background
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Abbreviation: TRAPPC8
Target Synonym: Trafficking protein particle complex subunit 8,TRAPPC8,Protein TRS85 homolog,KIAA1012
Background: The transport protein particle (TRAPP) complex was initially identified as a tethering factor for COPII vesicle. Subsequently, three forms (TRAPPI, II, and III) have been found and TRAPPIII has been reported to serve as a regulator in autophagy. This study investigates a new role of mammalian TRAPPIII in ciliogenesis. We found a ciliopathy protein, oral-facial-digital syndrome 1 (OFD1), interacting with the TRAPPIII-specific subunits TRAPPC8 and TRAPPC12. TRAPPC8 is necessary for the association of OFD1 with pericentriolar material 1 (PCM1).
- Molecular Weight
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Calculated MW: 16.5 kDa
Observed MW: 20 kDa
- UniProt
- Q9Y2L5-1
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