Smooth Muscle Actin Protein (AA 2-377) (His tag)
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- Target See all Smooth Muscle Actin (ACTA2) Proteins
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-377
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Smooth Muscle Actin protein is labelled with His tag.
- Sequence
- Cys 2-Phe 377
- Characteristics
- A DNA sequence encoding the Human ACTA2 protein (P62736) (Cys 2-Phe 377) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ACTA2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Alternative Name
- ACTA2 (ACTA2 Products)
- Synonyms
- AAT6 Protein, ACTSA Protein, MYMY5 Protein, GAMMA-ACTIN Protein, ACT Protein, ACTA3 Protein, ACTE Protein, ACTL3 Protein, ACTSG Protein, Act-4 Protein, Act4 Protein, SMGA Protein, 0610041G09Rik Protein, Actvs Protein, SMalphaA Protein, a-SMA Protein, alphaSMA Protein, wu:fb63d03 Protein, ASMA Protein, SMactin Protein, a-sma Protein, aat6 Protein, actsa Protein, mymy5 Protein, sm-actin Protein, ACTA2 Protein, actc1 Protein, ACT-4 Protein, asma Protein, ACTGE Protein, actin, alpha 2, smooth muscle, aorta Protein, actin, gamma 2, smooth muscle, enteric Protein, actin, alpha 2, smooth muscle, aorta L homeolog Protein, ACTA2 Protein, ACTG2 Protein, Actg2 Protein, Acta2 Protein, acta2 Protein, acta2.L Protein
- Background
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Abbreviation: ACTA2
Target Synonym: a actin,AAT6,Actin aortic smooth muscle,ACTSA,GIG46,Growth inhibiting gene 46,MYMY5
Background: Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic β- and γ-actin proteins are referred to as ""non-muscle"" actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility. The α-cardiac and α-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells.
- Molecular Weight
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Calculated MW: 41.25 kDa
Observed MW: 42 kDa
- UniProt
- P62736
- Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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