Nanog Protein (AA 94-162) (His tag)
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- Target See all Nanog (NANOG) Proteins
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 94-162
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Nanog protein is labelled with His tag.
- Sequence
- Lys 94-Ser 162
- Characteristics
- A DNA sequence encoding the Human NANOG protein (Q9H9S0) (Lys 94-Ser 162) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product NANOG Protein
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Nanog Homeobox (NANOG) (AA 2-305) protein (His tag)
NANOG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nanog Homeobox (NANOG) (AA 1-305) proteinNANOG Origin: Human Host: Escherichia coli (E. coli) > 90 % by SDS - PAGE SDS
Nanog Homeobox (NANOG) (AA 98-195) protein (GST tag)NANOG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Alternative Name
- NANOG (NANOG Products)
- Synonyms
- 2410002E02Rik Protein, ENK Protein, ecat4 Protein, NANOG Protein, hacp Protein, wu:fd19e04 Protein, wu:fd20a07 Protein, zgc:193933 Protein, Nanog homeobox Protein, nanog homeobox Protein, Nanog Protein, NANOG Protein, nanog Protein
- Background
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Abbreviation: NANOG
Target Synonym: Embryonic stem cell specific homeobox protein,ENK,FLJ12581,hNanog,Homeobox protein NANOG
Background: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation.
- Molecular Weight
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Calculated MW: 7.48 kDa
Observed MW: 12 kDa
- UniProt
- Q9H9S0
- Pathways
- Stem Cell Maintenance
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