MGEA5 Protein (AA 6-240) (His tag)
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- Target See all MGEA5 Proteins
- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 6-240
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MGEA5 protein is labelled with His tag.
- Sequence
- Ser 6-Lys 240
- Characteristics
- A DNA sequence encoding the Human OGA protein (O60502) (Ser 6-Lys 240) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MGEA5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
- Alternative Name
- OGA (MGEA5 Products)
- Synonyms
- MEA5 Protein, NCOAT Protein, OGA Protein, 2810009A20Rik Protein, 4833427O07Rik Protein, 5830447M11Rik Protein, AA408215 Protein, Hy5 Protein, Ncoat Protein, mKIAA0679 Protein, O-GLCNACASE Protein, cytochrome c oxidase subunit VIc Protein, meningioma expressed antigen 5 (hyaluronidase) Protein, COX6C Protein, MGEA5 Protein, Mgea5 Protein
- Background
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Abbreviation: OGA
Target Synonym: OGA,HEXC,KIAA0679,MEA5,MGEA5,Protein O-GlcNAcase
Background: Isoform 1:Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) . Does not bind acetyl-CoA and does not have histone acetyltransferase activity. Isoform 3 :Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1.
- Molecular Weight
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Calculated MW: 25.74 kDa
Observed MW: 25 kDa
- UniProt
- O60502
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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