HAVCR1 Protein (AA 21-245) (GST tag)

Catalog No. ABIN7505096

Product Details

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Protein Type: Recombinant

Protein Characteristics: AA 21-245

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HAVCR1 protein is labelled with GST tag.

Sequence: Ser 21-Ala 245

Characteristics: A DNA sequence encoding the Human KIM-1 protein (Q96D42) (Ser 21-Ala 245) was expressed with a N-GST tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Alternative Name: KIM-1 (HAVCR1 Products)

Synonyms: HAVCR Protein, HAVCR-1 Protein, KIM-1 Protein, KIM1 Protein, TIM Protein, TIM-1 Protein, TIM1 Protein, TIMD-1 Protein, TIMD1 Protein, Kim1 Protein, HAVCR1 Protein, LOC100226241 Protein, AI503787 Protein, Tim1 Protein, Timd1 Protein, hepatitis A virus cellular receptor 1 Protein, hepatitis A virus cellular receptor 1 homolog Protein, HAVCR1 Protein, Havcr1 Protein, LOC100226241 Protein

Background:

Abbreviation: KIM-1

Target Synonym: CD365;HACVR;HAVCR;HAVCR-1;KIM-1;KIM1;TIM;TIM-1;TIM1;TIMD-1;TIMD1

Background: HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

Molecular Weight:

Calculated MW: 49.64 kDa

Observed MW: 50 kDa

UniProt: Q96D42