GIP Protein (AA 22-153) (His tag)
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- Target See all GIP Proteins
- GIP (Gastric Inhibitory Polypeptide (GIP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-153
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GIP protein is labelled with His tag.
- Sequence
- Glu 22-Arg 153
- Characteristics
- A DNA sequence encoding the Human GIP protein (P09681) (Glu 22-Arg 153) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GIP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- GIP (Gastric Inhibitory Polypeptide (GIP))
- Alternative Name
- GIP (GIP Products)
- Synonyms
- GIP Protein, xgip Protein, Gludins Protein, RATGLUDINS Protein, gastric inhibitory polypeptide Protein, gastric inhibitory polypeptide L homeolog Protein, GIP Protein, gip Protein, Gip Protein, gip.L Protein
- Background
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Abbreviation: GIP
Target Synonym: gastric inhibitory polypeptide,GIP,Glucose-dependent Insulinotropic Polypeptide,Incretin
Background: Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of hormones. GIP, together with glucagon-like peptide-1 (GLP-1), belongs to the group of metabolic hormones called incretins that stimulate a decrease in blood glucose levels. GIP is derived from a 153-amino acid pro-protein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide. Engagement of Gastric inhibitory polypeptide receptors (GIPR) by GIP on pancreatic beta cells activates adenylate cyclase to regulate insulin compensation in the presence of high circulating glucose.
- Molecular Weight
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Calculated MW: 14.41 kDa
Observed MW: 18 kDa
- UniProt
- P09681
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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