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GIP Protein (AA 22-153) (His tag)

GIP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505083
  • Target See all GIP Proteins
    GIP (Gastric Inhibitory Polypeptide (GIP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-153
    Origin
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GIP protein is labelled with His tag.
    Sequence
    Glu 22-Arg 153
    Characteristics
    A DNA sequence encoding the Human GIP protein (P09681) (Glu 22-Arg 153) was expressed with a N-His tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product GIP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    GIP (Gastric Inhibitory Polypeptide (GIP))
    Alternative Name
    GIP (GIP Products)
    Synonyms
    GIP Protein, xgip Protein, Gludins Protein, RATGLUDINS Protein, gastric inhibitory polypeptide Protein, gastric inhibitory polypeptide L homeolog Protein, GIP Protein, gip Protein, Gip Protein, gip.L Protein
    Background

    Abbreviation: GIP

    Target Synonym: gastric inhibitory polypeptide,GIP,Glucose-dependent Insulinotropic Polypeptide,Incretin

    Background: Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of hormones. GIP, together with glucagon-like peptide-1 (GLP-1), belongs to the group of metabolic hormones called incretins that stimulate a decrease in blood glucose levels. GIP is derived from a 153-amino acid pro-protein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide. Engagement of Gastric inhibitory polypeptide receptors (GIPR) by GIP on pancreatic beta cells activates adenylate cyclase to regulate insulin compensation in the presence of high circulating glucose.

    Molecular Weight

    Calculated MW: 14.41 kDa

    Observed MW: 18 kDa

    UniProt
    P09681
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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