AZGP1 Protein (AA 148-298) (His tag)

Catalog No. ABIN7505082

Product Details

Target: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Protein Type: Recombinant

Protein Characteristics: AA 148-298

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This AZGP1 protein is labelled with His tag.

Sequence: Asn 148-Ser 298

Characteristics: A DNA sequence encoding the Human AZGP1 protein (P25311) (Asn148-Ser298) was expressed with a N-His .

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

Alternative Name: AZGP1 (AZGP1 Products)

Synonyms: Zag Protein, ZA2G Protein, ZAG Protein, ZA2GA Protein, Zna2gp Protein, alpha-2-glycoprotein 1, zinc Protein, alpha-2-glycoprotein 1, zinc-binding Protein, Azgp1 Protein, AZGP1 Protein

Background:

Abbreviation: AZGP1

Target Synonym: Zinc-Alpha-2-Glycoprotein,Zn-Alpha-2-GP,Zn-Alpha-2-Glycoprotein,AZGP1,ZAG,ZNGP1

Background: Zinc-α-2-Glycoprotein (AZGP1) can be found in blood plasma, seminal plasma, urine, sweat, saliva, liver, and epithelial cells of various human glands. AZGP1 has been proposed in the regulation of body weight, and the melanin production by normal and malignant melanocytes. AZGP1 stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. AZGP1 has been reported to stimulate lipid breakdown and may have an important role in lipid homeostasis. Mature human AZGP1 consists of one MHC class I antigen region and a C2-type Ig-like domain. AZGP1 has two alternate splice forms, one shows a 66 amino acids substitution for the C-terminal 30 amino acids, the other one shows a nine Lys substitution for amino acid 151-298.

Molecular Weight:

Calculated MW: 16.5 kDa

Observed MW: 22 kDa

UniProt: P25311

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process