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BAG3 Protein (AA 421-498) (GST tag)

BAG3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505080
  • Target See all BAG3 Proteins
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 421-498
    Origin
    • 4
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This BAG3 protein is labelled with GST tag.
    Sequence
    Gly 421-Ala 498
    Characteristics
    A DNA sequence encoding the Human BAG3 protein (O95817) (Gly 421-Ala 498) was expressed with a N-GST tag.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product BAG3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Alternative Name
    BAG3 (BAG3 Products)
    Synonyms
    bag3-A Protein, MGC53113 Protein, zgc:100859 Protein, BAG3 Protein, ATBAG3 Protein, BCL-2-associated athanogene 3 Protein, T28J14.160 Protein, T28J14_160 Protein, BAG-3 Protein, BIS Protein, CAIR-1 Protein, MFM6 Protein, AA407278 Protein, Bis Protein, mg638 Protein, BCL2 associated athanogene 3 L homeolog Protein, BCL2-associated athanogene 3 Protein, BCL2 associated athanogene 3 Protein, BCL-2-associated athanogene 3 Protein, Bcl2-associated athanogene 3 Protein, bag3.L Protein, bag3 Protein, BAG3 Protein, Bag3 Protein
    Background

    Abbreviation: BAG3

    Target Synonym: BAG-3,Bag3,BAG3

    Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

    Molecular Weight

    Calculated MW: 33.47 kDa

    Observed MW: 35 kDa

    UniProt
    O95817
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