BAG3 Protein (AA 421-498) (GST tag)
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- Target See all BAG3 Proteins
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 421-498
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BAG3 protein is labelled with GST tag.
- Sequence
- Gly 421-Ala 498
- Characteristics
- A DNA sequence encoding the Human BAG3 protein (O95817) (Gly 421-Ala 498) was expressed with a N-GST tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BAG3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Alternative Name
- BAG3 (BAG3 Products)
- Synonyms
- bag3-A Protein, MGC53113 Protein, zgc:100859 Protein, BAG3 Protein, ATBAG3 Protein, BCL-2-associated athanogene 3 Protein, T28J14.160 Protein, T28J14_160 Protein, BAG-3 Protein, BIS Protein, CAIR-1 Protein, MFM6 Protein, AA407278 Protein, Bis Protein, mg638 Protein, BCL2 associated athanogene 3 L homeolog Protein, BCL2-associated athanogene 3 Protein, BCL2 associated athanogene 3 Protein, BCL-2-associated athanogene 3 Protein, Bcl2-associated athanogene 3 Protein, bag3.L Protein, bag3 Protein, BAG3 Protein, Bag3 Protein
- Background
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Abbreviation: BAG3
Target Synonym: BAG-3,Bag3,BAG3
Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.
- Molecular Weight
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Calculated MW: 33.47 kDa
Observed MW: 35 kDa
- UniProt
- O95817
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